I use a little sucralose in my tea. I can't see where it harms anything? To compare it with a substitute with known problems, like aspartame, is confusing, in my opinion. Being a devil's advocate, I might ask if greek yogurt, containing strawberries and splenda, is good for your gut biome?

And remember, sugar feeds the yeast and fungi more than the good bacteria.

While splenda might not be a positive, its help in keeping people off of sugar is priceless. In my opinion, at least.